Sunday, 21 January 2018    HomeAbout UsContact Us    









You are here: Home Research Nigella Sativa (Black Seed)


Potential Immunomodulation Effect of the Extract of Nigella Sativa on Ovalbumin Sensitized Guinea Pigs
Posted by Admin, Senior Editor in Nigella Sativa (Black Seed)
Authored by PubMed
Topics: Nigella Sativa Black Seed

  Mail To Friend    Printer Friendly Bookmark and Share

Boskabady MH, Keyhanmanesh R, Khameneh S, Doostdar Y, Khakzad MR. Potential immunomodulation effect of the extract of nigella sativa on ovalbumin sensitized guinea pigs. 1. J Zhejiang Univ Sci B. 2011 Mar;12(3):201-9.
Several different pharmacological effects have been described for nigella sativa (Siah-Daneh), including an anti-inflammatory effect. In the present study, the effect of the extract of N. sativa on lung pathology and blood interleukin-4 (IL-4) and interferon-? (IFN-?) of sensitized guinea pigs was examined. Three groups (n=8 for each group) of guinea pigs sensitized to ovalbumin (OA) were given drinking water alone, and drinking water containing low and high concentrations of the plant extract, respectively. The animals of the control group (n=8) were treated with saline instead of OA and were given drinking water. The pathological changes of the lung, including infiltration of eosinophils and lymphocytes, local epithelial necrosis, the presence of oedema, thickening of the basement membrane, smooth muscle layer hypertrophy, mucosal secretion, and the presence of mucosal plug, and blood IL-4 and IFN-? of sensitized guinea pigs were evaluated. The lungs of the sensitized group showed significant pathological changes (P<0.001). Blood IL-4 and IFN-? were increased in sensitized animals compared to the controls (P<0.01 and P<0.001, respectively). Treatment of sensitized animals with the extract led to a significant decrease in pathological changes of the lung (P<0.01 to P<0.001), except for the oedema in the sensitized group treated with low concentration of the extract, but an increased IFN-?. These results confirm a preventive effect of N. sativa extract on lung inflammation of sensitized guinea pigs.


Link to this article:   Show: HTML LinkFull LinkShort Link
Share or Bookmark this page: You will need to have an account with the selected service in order to post links or bookmark this page.

                 
  
Subscribe via RSS or email:
Follow us through RSS or email. Click the RSS icon to subscribe to our feed.

     
  

Related Articles:
Add a Comment
You must be registered and logged in to comment.





Visit Vaccines.Me for information and education on vaccination.


Latest Articles
Some Notes of Advice on Health, Disease and 'Medicine'
Cooking With Vegetable Oils Releases Toxic Cancer-Causing Chemicals, Say Experts
Cancer Simplified: Part 5 - The Initiators and Promoters of Cancer
Cancer Simplified: Part 4 - The Immune System's In-Built Anti-Cancer Mechanism
Cancer Simplified: Part 3 - Cancer Is Simply a Failure of the Immune System
Cancer Simplified: Part 2 - An Analogy for Different Perceptions About Treatment of Cancer
Cancer Simplified: Part 1 - What Is Cancer and How Does It Develop?
Honey and Anti-Biotic Resistance: A New Approach!
On the Rejection of Hijaamah by the Physicians (Shaykh Muhammad Bin Ibraaheem Aal Al-Shaykh)
How to Limit Efffects of Bisphenol-A Upon Children

Pages
No pages found.

Most Popular
Garlic, Honey and Apple Cider Vinegar: Must Have Excellent Home Remedy
How To Eat Fruit Properly
Rocket: A Spicy Salad Leaf With Potent Health Benefits
Ibn al-Qayyim: Henna Has Many Benefits from Treating Headaches to Burns
Why We Need Protein in our Diets
Talbina: Relaxation For the Heart of the Sick Person
Five Superfoods You Should Be Eating Everyday
Deodorant And Anti-Perspirant Dangers - Do You Know What You're Putting Under Your Armpits?
The Different Kinds Of Exercises Your Body Needs
What Foods Are Good For Your Eyesight?

Archives (View more)
2016 • January
2015 • November
2014 • March
2014 • February
2013 • October
2012 • October
2012 • August
2012 • January
2011 • December
2011 • November
2011 • October
2011 • September


Copyright © 2018 . All rights reserved. RSSTagsPrivacyLegal and Terms of Use LearnArabic.Com