Sunday, 23 November 2014    HomeAbout UsContact Us    









You are here: Home Research


Current Nutraceuticals in the Management of Osteoarthritis: A Review
Posted by Admin, Senior Editor in Research
Authored by PubMed
Topics: Pomegranate

  Mail To Friend    Printer Friendly Bookmark and Share



Akhtar N, Haqqi TM. Current nutraceuticals in the management of osteoarthritis: a review. 1. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):181-207.
Osteoarthritis (OA) is a progressive degenerative joint disease that has a major impact on joint function and quality of life. Nutraceuticals and dietary supplements derived from herbs have long been used in traditional medicine and there is considerable evidence that nutraceuticals may play an important role in inflammation and joint destruction in OA. We review the biological effects of some medicinal fruits and herbs - pomegranate, green tea, cat's claw, devil's claw, ginger, Indian olibaum, turmeric and ananas - in an attempt to understand the pivotal molecular targets involved in inflammation and the joint destruction process and to summarize their toxicities and efficacy for OA management. So far there is insufficient reliable evidence on the effectiveness of ginger, turmeric and ananas. Pomegranate and green tea only have preclinical evidence of efficacy due to the lack of clinical data. In vivo and clinical studies are required to understand their targets and efficacy in OA. Limited in vitro and in vivo evidence is available for cat's claw and Indian olibaum. More extensive studies are required before long-term controlled trials of whole cat's claw and Indian olibaum extracts, or isolated active compounds, are carried out in patients with OA to determine their long-term efficacy and safety. Devil's claw has not been rigorously tested to determine its antiarthritic potential in in vitro and in vivo models. There is strong clinical evidence of the effectiveness of devil's claw in pain reduction. However, high-quality clinical trials are needed to determine its effectiveness. No serious side effects have been reported for any fruits and herbs. Overall, these studies identify and support the use of nutraceuticals to provide symptomatic relief to patients with OA and to be used as adjunct therapy for OA management. More high-quality trials are needed to provide definitive answers to questions related to their efficacy and safety for OA prevention and/or treatment.


Link to this article:   Show: HTML LinkFull LinkShort Link
Share or Bookmark this page: You will need to have an account with the selected service in order to post links or bookmark this page.

                 
  
Subscribe via RSS or email:
Follow us through RSS or email. Click the RSS icon to subscribe to our feed.

     
  

Related Articles:
Add a Comment
You must be registered and logged in to comment.





Visit Vaccines.Me for information and education on vaccination.


Latest Articles
Honey and Anti-Biotic Resistance: A New Approach!
On the Rejection of Hijaamah by the Physicians (Shaykh Muhammad Bin Ibraaheem Aal Al-Shaykh)
How to Limit Efffects of Bisphenol-A Upon Children
The Harmful Effects of Bisphenol-A on the Body and Its Biochemistry
Nestle Attempting to Patent Nigella Sativa ((Black Seed)
Ajwa Dates Contain Cancer-Preventing Property
Eat Less and Live Healthier and Longer?
Efficacy of a Herbal Extract Gel in the Treatment of Gingivitis: A Clinical Study
Pomegranate Materials Inhibit Flagellin Gene Expression and Flagellar-Propelled Motility of Uropathogenic Escherichia Coli Strain CFT073
Anti-Inflammatory Effects of Pomegranate (Punica Granatum L.) Husk Ellagitannins in Caco-2 Cells, an in Vitro Model of Human Intestine

Pages
No pages found.

Most Popular
Garlic, Honey and Apple Cider Vinegar: Must Have Excellent Home Remedy
How To Eat Fruit Properly
Ibn al-Qayyim: Henna Has Many Benefits from Treating Headaches to Burns
Rocket: A Spicy Salad Leaf With Potent Health Benefits
Why We Need Protein in our Diets
Five Superfoods You Should Be Eating Everyday
Deodorant And Anti-Perspirant Dangers - Do You Know What You're Putting Under Your Armpits?
What Foods Are Good For Your Eyesight?
The Different Kinds Of Exercises Your Body Needs
Foods for Healthy Hair

Archives (View more)
2014 • March
2014 • February
2013 • October
2012 • October
2012 • August
2012 • January
2011 • December
2011 • November
2011 • October
2011 • September
2011 • August
2011 • July


Copyright © 2014 . All rights reserved. RSSTagsPrivacyLegal and Terms of Use Learn the Arabic Alphabet