Saturday, 25 May 2013    HomeAbout UsContact Us    









You are here: Home Research


Reversal of Memory Deficits by Coriandrum Sativum Leaves in Mice
Posted by Admin, Senior Editor in Research
Authored by PubMed
Topics: Cilantro Coriander

  Mail To Friend    Printer Friendly Bookmark and Share

Coriander (Coriandrum sativum), also known as cilantro, Chinese parsley or dhania, is an annual herb in the family Apiaceae. Coriander is native to regions spanning from southern Europe and North Africa to southwestern Asia.

Mani V, Parle M, Ramasamy K, Abdul Majeed AB. Reversal of memory deficits by Coriandrum sativum leaves in mice. 1. J Sci Food Agric. 2011 Jan 15;91(1):186-92. doi: 10.1002/jsfa.4171. Epub 2010 Sep 17.
BACKGROUND: Coriandrum sativum L., commonly known as coriander and belonging to the family Apiaceae (Umbelliferae), is cultivated throughout the world for its nutritional value. The present study was undertaken to investigate the effects of fresh Coriandrum sativum leaves (CSL) on cognitive functions, total serum cholesterol levels and brain cholinesterase activity in mice. In this study, CSL (5, 10 and 15% w/w of diet) was fed orally with a specially prepared diet for 45 days consecutively to experimental animals. Elevated plus-maze and passive avoidance apparatus served as the exteroceptive behavioral models for testing memory. Diazepam, scopolamine and ageing-induced amnesia served as the interoceptive behavioral models. RESULTS: CSL (5, 10 and 15% w/w of diet) produced a dose-dependent improvement in memory scores of young as well as aged mice. CSL also reversed successfully the memory deficits induced by scopolamine (0.4 mg kg(-1), i.p.) and diazepam (1 mg kg(-1), i.p.). Interestingly, brain cholinesterase activity and serum total cholesterol levels were considerably reduced by CSL administration in daily diets concomitantly for 45 days. CONCLUSION: CSL may be a useful remedy in the management of Alzheimer's disease on account of its multifarious effects such as, memory-improving property, cholesterol-lowering property and anticholinesterase activity.


Link to this article:   Show: HTML LinkFull LinkShort Link
Share or Bookmark this page: You will need to have an account with the selected service in order to post links or bookmark this page.

                 
  
Subscribe via RSS or email:
Follow us through RSS or email. Click the RSS icon to subscribe to our feed.

     
  

Related Articles:
Add a Comment
You must be registered and logged in to comment.





Visit Vaccines.Me for information and education on vaccination.


Latest Articles
Eat Less and Live Heathier and Longer?
Efficacy of a Herbal Extract Gel in the Treatment of Gingivitis: A Clinical Study
Pomegranate Materials Inhibit Flagellin Gene Expression and Flagellar-Propelled Motility of Uropathogenic Escherichia Coli Strain CFT073
Anti-Inflammatory Effects of Pomegranate (Punica Granatum L.) Husk Ellagitannins in Caco-2 Cells, an in Vitro Model of Human Intestine
The Effect of Commiphora Molmol (Myrrh) in Treatment of Trichomoniasis Vaginalis Infection
Aldose Reductase Inhibitory Activity and Antioxidant Capacity of Pomegranate Extracts
Pomegranate Peel and Fruit Extracts: A Review of Potential Anti-Inflammatory and Anti-Infective Effects
Dietary Polyphenols and Mechanisms of Osteoarthritis
Pomegranate Phytoconstituents Blunt the Inflammatory Cascade in a Chemically Induced Rodent Model of Hepatocellular Carcinogenesis
Current Nutraceuticals in the Management of Osteoarthritis: A Review

Pages
No pages found.

Most Popular
Garlic, Honey and Apple Cider Vinegar: Must Have Excellent Home Remedy
How To Eat Fruit Properly
Ibn al-Qayyim: Henna Has Many Benefits from Treating Headaches to Burns
Rocket: A Spicy Salad Leaf With Potent Health Benefits
Why We Need Protein in our Diets
Five Superfoods You Should Be Eating Everyday
Deodorant And Anti-Perspirant Dangers - Do You Know What You're Putting Under Your Armpits?
What Foods Are Good For Your Eyesight?
Foods for Healthy Hair
The Different Kinds Of Exercises Your Body Needs

Archives (View more)
2012 • October
2012 • August
2012 • January
2011 • December
2011 • November
2011 • October
2011 • September
2011 • August
2011 • July
2011 • June
2011 • May
2011 • April


Copyright © 2013 . All rights reserved. RSSTagsPrivacyLegal and Terms of Use