Ameliorative Effects of Herbal Combinations in Hyperlipidemia


By PubMed
Posted by Admin on Wednesday, August, 15 2012 and filed under Ashwagandha
Key topics: Ashwagandha Withania Somnifera

Visavadiya NP, Narasimhacharya AV. Ameliorative effects of herbal combinations in hyperlipidemia. 1. Oxid Med Cell Longev. 2011;2011:160408. doi: 10.1155/2011/160408. Epub 2011 Sep 15.

The roots of Glycyrrhiza glabra, Withania somnifera, asparagus racemosus, and Chlorophytum borivilianum and seeds of Sesamum indicum are ayurvedic medicinal plants used in India to treat several ailments. Our previous studies indicated that these plants possess hypolipidemic and antioxidant potential. The present study was aimed at investigating the composite effects of these plants on hypercholesterolemic rats. Three different combinations (5?gm%, given for four weeks) used in this study effectively reduced plasma and hepatic lipid profiles and increased fecal excretion of cholesterol, neutral sterol, and bile acid along with increasing the hepatic HMG-CoA reductase activity and bile acid content in hypercholesterolemic rats. Further, all three combinations also improved the hepatic antioxidant status (catalase, SOD, and ascorbic acid levels) and plasma total antioxidant capacity with reduced hepatic lipid peroxidation. Overall, combination I had the maximum effect on hypercholesterolemic rats followed by combinations II and III due to varying concentrations of the different classes of phytocomponents.


Return to Home

Health, fitness and longevity
 Based upon the principles of health
 in the Qur'an and Prophetic Traditions.
HealthyMuslim.Com

There are two bounties in which
most people lose out: good health
and free time. Al-Bukhari.
The information on this site is provided for educational purposes only. It is not intended as a substitute for professional advice of any kind.