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The relevant extracts from the report:
We purposely fluoridate a range of everyday products, notably toothpaste and drinking water, because for decades we have believed that fluoride in small doses has no adverse effects on health to offset its proven benefits in preventing dental decay. But more and more scientists are now seriously questioning the benefits of fluoride, even in small amounts...
Fluoride was first used to fight dental cavities in the 1940s, its effectiveness defended on two grounds:
- fluoride inhibits enzymes that breed acid-producing oral bacteria whose acid eats away tooth enamel. This observation is valid, but some scientists now believe that the harmful impact of fluoride on other useful enzymes far outweighs the beneficial effect on caries prevention.
- fluoride ions bind with calcium ions, strengthening tooth enamel as it forms in children. Many researchers now consider this more of an assumption than fact, because of conflicting evidence from studies in India and several other countries over the past 10 to 15 years. Nevertheless, agreement is universal that excessive fluoride intake leads to loss of calcium from the tooth matrix, aggravating cavity formation throughout life rather than remedying it, and so causing dental fluorosis. Severe, chronic and cumulative overexposure can cause the incurable crippling of skeletal fluorosis.
.. Chronic intake of excessive fluoride can lead to the severe and permanent bone and joint deformations of skeletal fluorosis. Early symptoms include sporadic pain and stiffness of joints: headache, stomach-ache and muscle weakness can also be warning signs. The next stage is osteosclerosis (hardening and calcifying of the bones), and finally the spine, major joints, muscles and nervous system are damaged.
Source: From Unicef , "Water Environment and Sanitation: Fluoride in water: An overview".