The study compared the effects of a typical diet and a diet containing walnuts across the lifespan: through the mother from conception through weaning, and then through eating the food directly. The amount of walnut in the test diet equates to about 2 ounces a day for humans.
During the study period, the group whose diet included walnut at both stages developed Breast cancer at less than half the rate of the group with the typical diet. In addition, the number of tumors and their sizes were significantly smaller.
"These reductions are particularly important when you consider that the mice were genetically programmed to develop cancer at a high rate," The lead author said. "We were able to reduce the risk for cancer even in the presence of a pre-existing genetic mutation."
The paper notes that dietary modification studies do not show whether benefits result from what is added to a diet or what is removed. In this case, adding healthy fat and other components meant that unhealthy fat was reduced to keep total dietary fat balanced in the mice. The author said other studies have clearly shown, however, that multiple ingredients in walnuts reduce the risk of cancer or slow its growth.
Using genetic analysis, the study found that the walnut-containing diet changed the activity of multiple genes that are relevant to Breast cancer in both mice and humans. Other testing showed that increases in omega-3 fatty acids did not fully account for the anti-cancer effect, and found that tumor growth decreased when dietary Vitamin E increased.
"Food is important medicine in our diet,"
"What we put into our bodies makes a big difference - it determines how the body functions, our reaction to illness and health. The simple stuff really works: eat right, get off the couch, and turn off the TV.
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