Monday, 23 July 2018    HomeAbout UsContact Us    









You are here: Home Research Nigella Sativa (Black Seed)


Primary Human Monocyte Differentiation Regulated by Nigella Sativa Pressed Oil
Posted by Admin, Senior Editor in Nigella Sativa (Black Seed)
Authored by PubMed
Topics: Nigella Sativa Black Seed Atherosclerosis

  Mail To Friend    Printer Friendly Bookmark and Share

Mat MC, Mohamed AS, Hamid SS. Primary human monocyte differentiation regulated by nigella sativa pressed oil. 1. Lipids health Dis. 2011 Nov 21;10:216.
BACKGROUND: Oxidized low density lipoprotein plays an important role in development of foam cells in atherosclerosis. The study was focused on regulation of primary human monocyte growth and CD11b expression in presence of nigella sativa oil. METHODS: Primary human monocytes were isolated from whole blood and grown at 37?C and 5% CO? saturation for five days prior to treatment with nigella sativa oil. The cells were plated and washed before treatment with ox-LDL (10 ?g/ml) as positive control and combined treatment of ox-LDL (10 ?g/ml) and (140 ng/ml) nigella sativa oil. The growth progression was monitored every 24 hours for 3 days. RESULTS: Macrophages showed reduced growth in comparison to monocytes 24 hours after treatment with nigella sativa oil. The mean cell diameter was significantly different between untreated and treated condition in monocytes and macrophages (p < 0.001). Similarly, intracellular lipid accumulation was hindered in combined treatment with nigella sativa oil. This was further supported by cell surface expression analysis, where CD11b was markedly reduced in cells treated with combination oxLDL and nigella sativa oil compared to oxLDL alone. More cells differentiated into macrophage-like cells when monocytes were supplemented with oxidized LDL alone. CONCLUSIONS: The finding provides preliminary evidence on regulation of cell growth and differentiation in monocyte and monocyte-derived macrophages by nigella sativa oil. Further investigations need to be conducted to explain its mechanism in human monocyte.


Link to this article:   Show: HTML LinkFull LinkShort Link
Share or Bookmark this page: You will need to have an account with the selected service in order to post links or bookmark this page.

                 
  
Subscribe via RSS or email:
Follow us through RSS or email. Click the RSS icon to subscribe to our feed.

     
  

Related Articles:
Add a Comment
You must be registered and logged in to comment.





Visit Vaccines.Me for information and education on vaccination.


Latest Articles
Some Notes of Advice on Health, Disease and 'Medicine'
Cooking With Vegetable Oils Releases Toxic Cancer-Causing Chemicals, Say Experts
Cancer Simplified: Part 5 - The Initiators and Promoters of Cancer
Cancer Simplified: Part 4 - The Immune System's In-Built Anti-Cancer Mechanism
Cancer Simplified: Part 3 - Cancer Is Simply a Failure of the Immune System
Cancer Simplified: Part 2 - An Analogy for Different Perceptions About Treatment of Cancer
Cancer Simplified: Part 1 - What Is Cancer and How Does It Develop?
Honey and Anti-Biotic Resistance: A New Approach!
On the Rejection of Hijaamah by the Physicians (Shaykh Muhammad Bin Ibraaheem Aal Al-Shaykh)
How to Limit Efffects of Bisphenol-A Upon Children

Pages
No pages found.

Most Popular
Garlic, Honey and Apple Cider Vinegar: Must Have Excellent Home Remedy
How To Eat Fruit Properly
Rocket: A Spicy Salad Leaf With Potent Health Benefits
Ibn al-Qayyim: Henna Has Many Benefits from Treating Headaches to Burns
Why We Need Protein in our Diets
Talbina: Relaxation For the Heart of the Sick Person
Five Superfoods You Should Be Eating Everyday
Deodorant And Anti-Perspirant Dangers - Do You Know What You're Putting Under Your Armpits?
The Different Kinds Of Exercises Your Body Needs
What Foods Are Good For Your Eyesight?

Archives (View more)
2016 • January
2015 • November
2014 • March
2014 • February
2013 • October
2012 • October
2012 • August
2012 • January
2011 • December
2011 • November
2011 • October
2011 • September


Copyright © 2018 . All rights reserved. RSSTagsPrivacyLegal and Terms of Use Quick Way to Learn Arabic Alphabet good resource